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J. Kappler, Ph.D. & P. Marrack, Ph.D. Research Laboratory |
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Wang Y, Becker D, Vass T, White J, Marrack P, Kappler
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induces innate immune responses through macrophage and mast cell sensors, but
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CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire.
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DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. 2008. Nedd4
augments the adaptive immune response by promoting ubiquitin-mediated
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major histocompatibility complex proteins. Curr Opin Immunol 20: 203-7. Scott-Browne
JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler
J, Marrack P, Gapin L. 2007. Germline-encoded recognition of
diverse glycolipids by natural killer T cells. Nat Immunol 8: 1105-13. Peyerl FW,
Dai S, Murphy GA, Crawford F, White J, Marrack P, Kappler JW. 2007. Elucidation
of some Bax conformational changes through crystallization of an
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does not have to adopt its final form to drive T cell death. J Exp Med 203: 1147-52. Willis RA,
Kappler JW, Marrack PC. 2006. CD8 T cell competition for
dendritic cells in vivo is an early event in activation. Proc Natl Acad Sci U S A 103: 12063-8. Robertson JM,
MacLeod M, Marsden VS, Kappler JW, Marrack P. 2006. Not all CD4+ memory T cells are
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Bim, breaks B cell anergy. J Exp
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Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J,
Marrack P, Yang B. 2006. Ndfip1 protein promotes the
function of itch ubiquitin ligase to prevent T cell activation and T helper 2
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pool. Int Arch Allergy Immunol
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and bone marrow cells in 1966: where did we go from there? J Allergy Clin Immunol 117: 962-4. Wang Y,
Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. 2005. Using
a baculovirus display library to identify MHC class I mimotopes. Proc Natl Acad Sci U S A 102: 2476-81. Zhu Y,
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Kappler J, Marrack P. 2004. Constitutive association of the
proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells.
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receptor stimulation. Proc Natl
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cell survival but not precursor B cell differentiation in the absence of
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Cambier JC, Kappler J, Marrack P, Swanson BJ. 2003. Mast cell-dependent migration of
effector CD8+ T cells through production of leukotriene B4. Nat Immunol 4: 974-81. Yassai M,
Ammon K, Goverman J, Marrack P, Naumov Y, Gorski J. 2002. A
molecular marker for thymocyte-positive selection: selection of CD4
single-positive thymocytes with shorter TCRB CDR3 during T cell development.
J Immunol 168: 3801-7. Veng LM,
Bjugstad KB, Freed CR, Marrack P, Clarkson ED, Bell KP, Hutt C, Zawada WM. 2002. Xenografts
of MHC-deficient mouse embryonic mesencephalon improve behavioral recovery in
hemiparkinsonian rats. Cell
Transplant 11: 5-16. Swanson BJ,
Murakami M, Mitchell TC, Kappler J, Marrack P. 2002. RANTES production by memory
phenotype T cells is controlled by a posttranscriptional, TCR-dependent process.
Immunity 17: 605-15. Myrick C,
DiGuisto R, DeWolfe J, Bowen E, Kappler J, Marrack P, Wakeland EK. 2002. Linkage
analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2.
Genes Immun 3: 144-50. Murakami M,
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the control of memory CD8+ T cells. Proc Natl Acad Sci U S A 99: 8832-7. Mitchell TC,
Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW,
Marrack P. 2002. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants
with adjuvant-induced T cell survival. Ann N Y Acad Sci 975: 114-31. http://www3.interscience.wiley.com/journal/118947501/abstract Wilson N,
Fremont D, Marrack P, Kappler J. 2001. Mutations changing the kinetics
of class II MHC peptide exchange. Immunity
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Schaefer ML, Kappler JW, Marrack P, Kedl RM. 2001. Observation of antigen-dependent
CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol 214: 110-22. Schaefer BC,
Mitchell TC, Kappler JW, Marrack P. 2001. A novel family of retroviral vectors
for the rapid production of complex stable cell lines. Anal Biochem 297: 86-93. Mitchell TC,
Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack
P. 2001. Immunological adjuvants promote activated T cell survival via induction
of Bcl-3. Nat Immunol 2: 397-402.
Marrack P,
Kappler J, Kotzin BL. 2001. Autoimmune disease: why and where
it occurs. Nat Med 7:
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Bender J, Jordan M, Rees W, Robertson J, Schaefer BC, Kappler J. 2001. Major
histocompatibility complex proteins and TCRs: do they really go together like a
horse and carriage? J Immunol
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of T cell hybridomas. Methods
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Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. 2000. Activation-induced
inhibition of interleukin 6-mediated T cell survival and signal transducer and
activator of transcription 1 signaling. J Exp Med 191: 915-26. Meyer AL,
Trollmo C, Crawford F, Marrack P, Steere AC, Huber BT, Kappler J, Hafler DA. 2000. Direct
enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II
tetramers. Proc Natl Acad Sci U
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Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC,
Kappler J. 2000. Genomic-scale analysis of gene expression in resting and activated T
cells. Curr Opin Immunol 12:
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Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer
BC, Swanson B, Kappler J. 2000. Homeostasis of alpha beta TCR+ T
cells. Nat Immunol 1:
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Crawford F, Fremont D, Marrack P, Kappler J. 1999. Soluble class I MHC with
beta2-microglobulin covalently linked peptides: specific binding to a T cell
hybridoma. J Immunol 162:
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Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack
P. 1999. Activation changes the spectrum but not the diversity of genes
expressed by T cells. Proc Natl
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Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. 1999. Live
cell fluorescence imaging of T cell MEKK2: redistribution and activation in
response to antigen stimulation of the T cell receptor. Immunity 11: 411-21. |
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